Substance use disorders (SUDs) refer to a range of conditions related to the recurrent use of alcohol, drugs, or other substances that lead to significant clinical and functional impairment. These disorders have a substantial impact on individuals' health, well-being, and social functioning. They are often associated with long-lasting changes in brain networks involved in reward, executive function, and stress reactivity. Research has shown that substance misuse and substance use disorders, including addiction, have significant implications for public health and social issues. Substance use frequently accompanies suicide and suicide attempts, and individuals with substance use disorders are at an increased long-term risk of suicide.
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